Summary: Antibodies that bind residue K169 in the V2 region of the HIV-1 envelope correlated with reduced risk of infection in the RV144 vaccine trial but were restricted to two ED-motif-encoding light chain genes.Here, we identify an HIV-infected donor with high-titer V2 peptide-binding antibodies and isolate two antibody lineages (CAP228-16H/19F
Water-based fracturing fluids are among the most common fluid types used in hydraulic fracturing operations.However, these fluids tend to cause damage in water-sensitive formations.Foam comprises a small amount of base fluid, and compressible gas such as carbon dioxide and nitrogen has emerged as a more ecologically friendly option to fracture such
Introduction Impulsivity and compulsivity are natural behaviors controlled by brain mechanisms that are essential for survival in all species.Understanding these brain mechanisms may lead to targeted treatment strategies for these symptom domains when impulsivity and compulsivity become dysfunctional.Pathological impulsivity and compulsivity charac
The coronation of James II, a Catholic, brought about a profound political change in religious matters in the British Isles.At court, a Catholicizing process was introduced, supported by the monarch and the European diplomats who opened chapels in different parts of the city.However, this missionary effort had an unequal reception and caused a popu